I've done the "cast remove curse before entering combat" trick. What's great about it is that you cast "remove curse" out of combat but don't un-equip the weapon. This gives the character the ability to auto-switch from the cursed weapon if all of the enemies are out of melee range the next time combat is initiated.Just remember to cast remove curse immediately after combat ends.
I forgot a few times and had to wait until the baddies got into melee range. Once you get into the habit it's almost automatic that you cast it after every battle.
Spence